National Capability Database | Search Results

Bioactive device design, development and batch manufacture

Bioactive device design, development and batch manufacture

  • Clinical Delivery
  • Pre-clinical Testing
  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • Near-Patient Manufacture
  • Newcastle University
  • Wide range of additive manufacture, 3d printing and moulding technques to fabricate macro and micro porous bioactive structures in biopolymers (natural and synthetic), bioceramic and biocomposite materials.

    Ability to scale up to provide batches of hundreds of devices for device level mechanical and biological evaluation.

    Able to undertake device level characterisation of ... More info

    Bioactive material development

    Bioactive material development

  • Pre-clinical Testing
  • Product Manufacture
  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • Near-Patient Manufacture
  • Newcastle University
  • Expertise and laboratory scale facilities for polymer and ceramic synthesis, and for the assessment of their mechanical and biological properties using in vitro assays and a wide range of physical property tests (DMA, DSC, XRD, XPS, SEM, TEM, TOF-SIMS).

    Spray dry and extrusion facilities for the preparation of nanocomposites.

    A range of ... More info

    Biocompatibility/immunology of prosthetic wear particles and biomaterials

    Biocompatibility/immunology of prosthetic wear particles and biomaterials

  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • University of Leeds
  • Leeds has a unique capability in developing testing methods to understand the biological consequences of exposure to biomaterials for tissue replacement in the musculoskeletal system. Examples of Leeds’ range of capability include: development of biocompatibility assays for a range of biomaterials; understanding how wear debris particles of a medical device interact ... More info

    Biocomposite Manufacture

    Biocomposite Manufacture

  • Pre-clinical Testing
  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Stratified Design & Manufacture
  • University of Nottingham
  • UoN has extensive experience of manufacturing resorbable biocomposites reinforced with glass and glass-fibres within Composites Research Group. There are facilities for high pressure composite production via laminate stacking and heat pressing and also autoclave manufacture. At Nottingham we also have vast mechanical testing facilities.

    ... More info
    Characterisation of fibrous scaffolds and grafts

    Characterisation of fibrous scaffolds and grafts

  • Product Design
  • Research & Development
  • All
  • University of Leeds
  • A suite of instrumental methods are available specifically for the characterisation of fibre-based scaffolds and grafts to ensure satisfactory product performance and to aid in product design. Test facilities include pore size distribution, fibre orientation distribution, air and specific permeability, capillarity and liquid spreading, burst strength testing, tensile and cyclic ... More info

    Characterisation of Natural Biomaterial Properties

    Characterisation of Natural Biomaterial Properties

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • We have developed a range of testing methodologies in order to characterise the material properties of natural tissues. This includes tensile/compressive testing to failure, creep/stress relaxation testing, and suture pull-out testing, for a range of biological tissues such as heart valves, ligaments, tendons, bone-patellar-tendon-bone constructs, arteries, meniscus etc

    ... More info
    Computer modelling over the length scales of biomedical polymers and composites

    Computer modelling over the length scales of biomedical polymers and composites

  • Product Design
  • Research & Development
  • All
  • University of Bradford
  • Finite element modelling including modelling of nanoscale, through to meso scale using representative volume elements and simulation technologies to achieve macroscopic scale prediction for material or product performance.  This is complemented by extensive image analysis capabilities e.g. for nanofilled materials.

    [Dr P Caton-Rose, Prof J Sweeney, Prof P D Coates]

    ... More info
    Decellularisation process for animal tissue

    Decellularisation process for animal tissue

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • iMBE has extensive capability and know-how in a unique decellularisation process of animal tissues. Supported by an intellectual property portfolio on immunocompatible biomimetic natural scaffolds, and led by Professor Eileen Ingham in the Faculty of Biological Sciences, the University of Leeds are researching and developing functional soft tissue solutions for musculoskeletal ... More info

    Decellularisation process for human tissue

    Decellularisation process for human tissue

  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • University of Leeds
  • iMBE has extensive capability and know-how in a unique decellularisation process for human tissues. Supported by an intellectual property portfolio on immunocompatible biomimetic natural scaffolds, and led by Professor Eileen Ingham in the Faculty of Biological Sciences, the University of Leeds are researching and developing functional soft tissue solutions for musculoskeletal ... More info

    Determination of friction for hip implants

    Determination of friction for hip implants

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • To complement our pre-clinical wear simulation facilities we have capability to measure the friction of artificial and natural joints through a variety of methods, from simple geometrical configuration using a pin-on-plate simulator, to a pendulum friction simulator predominantly used for hip replacements, through to single station physiological anatomical hip and ... More info

    Determination of friction for knee implants

    Determination of friction for knee implants

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • To complement our pre-clinical wear simulation facilities we have capability to measure the friction of artificial and natural joints through a variety of methods, from simple geometrical configuration using a pin-on-plate simulator, to a pendulum friction simulator predominantly used for hip replacements, through to single station physiological anatomical hip and ... More info

    Development of analysis methods for decellularisation

    Development of analysis methods for decellularisation

  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • University of Leeds
  • Leeds has a unique capability in research towards clinical and commercial translation of biological scaffolds in musculoskeletal and cardiovascular applications. The expertise is in the development of functional processes and analysis methods of biological scaffolds. This is based upon experience and know-how of our investigators, and their understanding of tissues based ... More info

    Manufacture of Bulk and Porous microspheres

    Manufacture of Bulk and Porous microspheres

  • Clinical Delivery
  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • Near-Patient Manufacture
  • Stratified Design & Manufacture
  • University of Nottingham
  • Very recent developments at Nottingham have resulted in creation of a Platform Technology for manufacture of microspheres from glass, glass-ceramic and ceramics.

    ... More info
    Microfibre production

    Microfibre production

  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • University of Leeds
  • Pilot scale wet spinning and melt-spinning facilities enable manufacture of continous filaments from solution spun and polymer-melts, with and without nanoparticle inclusions. Continuous in-line manufacture is possible from multiple spinning orifices.

    ... More info
    Micromoulding of high precision miniature products with specific surface features

    Micromoulding of high precision miniature products with specific surface features

  • Clinical Delivery
  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • Stratified Design & Manufacture
  • University of Bradford
  • A second case of our ‘Process Structuring’ is micromoulding – high speed, high precision moulding of 3-d components typically with large surface area to volume ratios.  The Polymer IRC at Bradford houses the international Polymer Micro & Nano Technology laboratory with Wittman Battenfeld MicroPower (x2, each 15 tonne clamp force) ... More info

    Nanofibre fabrication

    Nanofibre fabrication

  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • Free-surface electrospinning capabilities are available for converting a large variety of biomaterials into fibres and webs suitable for integration in to prototype medical devices. The system enables spinning over small 5 x 5 cm areas up to continuous web manufacture across a c. 200 mm conveyor. Additionally, a FibeRio forcespinning ... More info

    Nanomaterial manufacture

    Nanomaterial manufacture

  • Pre-clinical Testing
  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • University of Nottingham
  • Nanomaterials in both slurry and dry forms. These nanomaterials can be in the form of metals, metal oxides, phosphates, carbonates, sulfides, hydroxides

    Morphology can be altered in some cases and particles sizes can be altered in almost all cases.

    most suitable materials for medical work include hydroxyapatite and calcium carbonates, SPIOS and ... More info

    Nonwoven scaffold/graft prototyping facility

    Nonwoven scaffold/graft prototyping facility

  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • University of Leeds
  • Based upon a working width of 0.2-1m, industrially applicable pilot-scale facilities are available for the manufacture of nonwovens using drylaid, wetlaid, spunmelt, hydroentangling, needling, chemical and thermal bond technologies enabling conversion of  preformed fibres of 0.5-100 microns diameter in to sheet products. This is the most comprehensive pilot production facility ... More info

    Phosphate-based glass and fibre production

    Phosphate-based glass and fibre production

  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Stratified Design & Manufacture
  • University of Nottingham
  • UoN has extensive experience of manufacturing resorbable glass and glass-fibres within the Centre for Innovative Structural Fibre Manufacture (CISFM). There are facilities for glass production, melt—drawn fibres and pre-form fibre manufacturing. At Nottingham we also have we also glass fibre mechanical testing facilities including a high temperature glass viscometer. The viscometer enables the ... More info

    Pre-clinical Wear Simulation : Material Screening

    Pre-clinical Wear Simulation : Material Screening

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • iMBE has extensive pre-clinical wear simulation facilities with in excess of 80 stations for studying tribology of hip, knee and spine arthroplasty bearing materials and cartilage repair interventions. At Leeds we can wear-test polymers and metals in a simple geometrical configuration, determining the wear gravimetrically. This pin on plate wear testing can ... More info

    Pre-clinical Wear Simulation: Hip testing capabilities

    Pre-clinical Wear Simulation: Hip testing capabilities

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • iMBE has extensive pre-clinical wear simulation facilities with in excess of 80 stations for studying tribology of hip, knee and spine arthroplasty bearing materials and cartilage repair interventions. Our Leeds facilities are capable of simulating a standard gait cycle using iMBE Standard Operating Procedures  iMBE profiles or ISO14242 profiles. Using iMBE ... More info

    Pre-clinical Wear Simulation: Knee testing capabilities

    Pre-clinical Wear Simulation: Knee testing capabilities

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Leeds
  • iMBE has extensive pre-clinical wear simulation facilities with in excess of 80 stations for studying tribology of hip, knee and spine arthroplasty bearing materials and cartilage repair interventions. At Leeds we can test to – and beyond – the ISO standard. Our capabilities have been developed to study malalignment such as ... More info

    Precision Manufacturing

    Precision Manufacturing

  • Pre-clinical Testing
  • Product Design
  • All
  • Stratified Design & Manufacture
  • University of Nottingham
  • The Precision Manufacturing Centre at the University of Nottingham has an extensive range of state of the art precision manufacturing technologies including micro milling, micro EDM and micro wire EDM and ultra precision metrology equipment which offers precision CMMs as well as surface analysis and measurement capabilities. The Centre is ISO9001:2008 accredited.

    ... More info
    Property gradient biomedical materials and products

    Property gradient biomedical materials and products

  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • University of Bradford
  • We have expertise in biomedical materials, and have programmes involving property gradient materials including hydrogels for joint repair, and use the processing techniques above to make novel property gradient materials; also 3-d printing for novel starting material combinations.

    In collaboration with Sichuan University, we can manufacture novel comminuted micro-blends of materials ... More info

    Solid Phase orientation of biomedical or inert polymers

    Solid Phase orientation of biomedical or inert polymers

  • Clinical Delivery
  • Product Design
  • Product Manufacture
  • Research & Development
  • All
  • Biological & Biomimetic Materials
  • Near-Patient Manufacture
  • Stratified Design & Manufacture
  • University of Bradford
  • The Polymer IRC at Bradford has unique worldwide experimental and modelling facilities for ‘process structuring’, in this first case for  deformation processing of polymers in the solid phase.  Our extensive range of processes, particularly die drawing (invented by us) allow us to obtain oriented materials in solid or hollow section ... More info