MeDe Innovation Third Annual Meeting: The Future of Manufacturing of Medical Devices

MeDe Innovation Third Annual Meeting: The Future of Manufacturing of Medical Devices

Date: January 28, 2016

Location: Centre for Life, Newcastle

MeDe Innovation Annual Conference 2016 –

The Future of Manufacturing of Medical Devices

MeDe Innovation (The EPSRC Centre for Innovative Manufacturing in Medical Devices) is addressing the future opportunities and challenges in the design and manufacture of medical devices.   Our innovative design and manufacturing advances centres around three research focus areas: implants, biomaterials and regenerative devices for the treatment of musculoskeletal disease; where there is a growing demand for increased precision to deliver improved reliability and outcomes of medical devices.   The centre activities are addressing two grand challenges:

  • Manufacturing at the point of need
  • Stratified design and manufacture

The global market for medical technologies is set to   exceed $500bn per year by 2018, with a UK industry base valued at £18bn per year. Musculoskeletal implants, biomaterials and the emerging field of regenerative devices are major strengths in the UK, addressing a global market estimated to grow to $75bn by 2020.   The needs of an ageing population, the expectations of fifty active years after fifty® and the growth in healthcare markets in developing economies provide a real opportunity for growth in this part of the medical device technology sector.   However there are increased expectations and demands for enhanced lifetimes, cost effectiveness, more consistent patient outcomes and improved reliability. Stratification and increased precision, leading to improved reliability, is a key challenge in all areas of medicine and future opportunity for medical devices.   As we approach the mid-term of MeDe innovation, the conference will report on progress and advances in research, innovation, and translation of its three focus areas:

  • New approaches to manufacturing at the point of need
  • Manufacturing regenerative devices, biological and biomimetic scaffolds
  • Stratified design and manufacture of orthopaedic implants

The conference will include presentations and posters from industry, regulators clinicians and academic researchers, panel discussions, poster pitches and networking opportunities.

Download a copy of the event programme (opens PDF)

Time Name
9.30 Registration   and networking (tea and coffee available)
9.55 Welcome   and introduction Professor   John Fisher, Centre Director

Session A: Manufacturing at the point of need –   Chaired by Professors Kenny Dalgarno and Phil Coates

10.00 Regenerative strategies in orthopaedics; right patient, right   treatment, right time Prof Andrew McCaskie – University of Cambridge
10.15 Manufacture and assembly of biopolymer-bioceramic hybrid   composites Miss Natacha Rodrigues – Newcastle University
10.30 Shape memory soft tissue fixations for arthroscopic delivery Dr Fin Caton-Rose – University of Bradford
10.45 Development of materials for arthroscopic delivery Mr Simon Partridge – Newcastle University
11.00 Design and fabrication of 3D printed POSS-nanocomposite-based   lumbar cage for spinal fusion Dr Tiziano Serra – University College London
11.15  Droplet based deposition for in clinic bioprinting Dr Matthew Benning – Newcastle University

1 minute poster elevator pitches

Harnessing micro-injection moulding and Poly-ether-ether-ketone   (PEEK) to manufacture orthopaedic trauma implants that resist microbial   colonisation Dr Maria Katsikogianni – University of Bradford
Processing and characterisation of novel bioceramic formulations   using indirect powder-based 3D printing technology Ms Elena Mancuso – Newcastle University
Cell encapsulation for bio-ink formulation Mr Ricardo Ribeiro – Newcastle University
Compression screws for the fixation of small bones and bone fragments   using biocompatible, bioresorbable, body-temperature reverting, plasticised   shape memory polymers Dr Brian Thomson – University of Bradford
Apatite-Wollastonite glass ceramic scaffolds for osteochondral   tissue engineering applications Miss Sotiria Toumpaniari – Newcastle University
Polyether ether ketone (PEEK) crystallisation phases analysis in   microinjection moulding for anterior cervical decompression and fusion Dr Cristina-Luminita Tuinea-Bobe – University of Bradford
Viscoelastic mechanical optimisation of functionally graded   cell-conducting materials for osteochondral implants Dr Peter Twigg – University of Bradford
Synthesis of tendon tissue-like grafts using a hybrid PHBV-Collagen   material Dr Sarah Upson – Newcastle University
Controlled release of antibacterial drugs through in-situ   crosslinked wet-spun collagen triple helices Dr Muhammad Tarik Arafat – University of Leeds
 The development of stratified acellular biological   scaffolds for osteochondral repair Dr Hazel Fermor – University of Leeds
Pre-clinical biomechanical evaluation of acellular biological   scaffolds for tissue repair and replacement in the knee joint Dr Anthony Herbert – University of Leeds
Novel porous structures with internally-coated surfaces Dr Andrew Kennedy – University of Nottingham
Development of 3D artificial niches for regenerative medicine Dr Ilida Ortega – University of Sheffield
Fabrication of electrospun poly(caprolactone)/strontium-substituted   bioactive glass composite membranes for bone tissue regeneration Dr Martin Eduardo Santocildes Romero – University of Sheffield
Resorbable, therapeutic ion leaching thin films for implant   osseointegration Mr Bryan Stuart – University of Nottingham
 Design of bespoke collagen hydrogels for chronic wound   care Dr Giuseppe Tronci – University of Leeds
The next generation of simulators for stratified pre-clinical   wear simulation of total knee replacements Dr Abdellatif Abdelgaied – University of Leeds
Enhanced preclinical testing of hip joint replacements Dr Murat Ali – University of Leeds
Manufacturing phosphate-glass fibre reinforced composite rods as   bioresorbable intramedullary nails Mr Fernando Barrera Betanzos – University of Nottingham
PEEK Optima® as an Alternative   Bearing Material to Cobalt Chrome in Total Knee Replacements Dr Raelene Cowie – University of Leeds
The determination of acetabular orientation: measured in   different coordinate systems Dr Xijin Hua –   University of Leeds
Subject-specific multi-validation of a Finite Element model of   cervical functional spinal units Dr Marlène Mengoni – University of Leeds
The combined effect of head and cup centres mismatch and   different cup inclination angles on the occurrence and severity of edge   loading and wear in hip replacement Mr Oscar O’Dwyer Lancaster-Jones – University of Leeds
Wear of a total ankle replacement Ms Alexandra Smyth – University of Leeds
11.55 MeDe   Innovation Network Update Rowan   Grant – MeDe Innovation National Outreach Manager

Lunch and poster viewing


12.30-13.00 Poster   presenters available from A7-B17
13.00-13.30 Poster   presenters available from B18-C11

Session B: Manufacturing regenerative devices,   biological and biomimetic scaffolds – Chaired by Professors  Paul Hatton and David Grant

Nanoparticles   and medical devices
13.30 Continuous   hydrothermal synthesis of new nanoscale hydroxyapatite morphologies Prof   Ed Lester – University of Nottingham
13.35 Integrated   molecular design of melt-processable bioresorbable engineering nanocomposites   for health-care Miss   Kirsty Walton – University of Nottingham
13.40 Rapid   mix preparation of biomimetic nanoscale hydroxyapatite for biomedical applications Dr   Caroline Wilcock – University of Sheffield
13.45 Biomimetic   nano-structured materials for bone repair and regeneration – Industrial perspective Dr   Becci Goodchild – Ceramisys Ltd
13.50 Continuous   hydrothermal synthesis of nanoparticles – Scaling up Dr   Selina Tang – Promethean Particles Ltd
Resorbable   composite research
13.55 Bioresorbable   composites for bone fracture repair applications Dr   Ifty Ahmed – University of Nottingham
14.07 Development   of bio-active glass products and production processes Dr   Malcolm Gledenning – Glass Technology Services Ltd
Spinal   medical devices
14.15 Trabecular   directionality in three dimensional remodelling of bone graft substitute in   cervical fusions Dr   Donal McNally – University of Nottingham
14.23 Porosity   measurements in three dimensional remodelling of bone graft substitute in   cervical fusions Dr   Scott Johnson – Cerapedics Inc
Surface   modification and scaffolds
14.30 Layer-by-layer:   a bioengineered tool to enhance specific biological activities at nanoscale Dr   Piergiorgio Gentile – Newcastle University
14.37 Hydroxyapatite   functionalised using a coupled heparin-binding peptide Mr   Joss Atkinson – University of Sheffield
14.44 Development   of 3D polymer scaffolds for biomedical applications; degradation and   compression properties Dr   Reda Felfel –
14.51 The   JRI approach to innovation in Med Tech Dr   Sarrawat Rehman – JRI Orthopaedics Ltd
15.00 Break   and poster viewing

Session C: Stratified design and manufacture of   orthopaedic implants – Chaired by Professors John Fisher  and Ruth Wilcox

15.30 Overview   of Challenge 1: Stratified design and manufacture of orthopaedic implants Prof   John Fisher – University of Leeds
15.35 Computational   modelling of patient variation in the spine: a route to stratified device   design and testing Prof   Ruth Wilcox and Prof Philippe Young – University of Leeds and Simpleware Ltd
15.45 Application   of a computational and experimental wear simulation approach to new product   development Louise   Jennings and Dr Adam Briscoe – University of Leeds and Invibio Ltd
15.55 Effect   of surgical variations on the function and tribological performance of hip   joint replacement Dr   Mazen Al Hajjar and Dr Jonathan Thompson – University of Leeds and DePuy   Synthes
16.05 Panel   discussion with Session C speakers
16.20 Closing   comments Prof   John Fisher

Life Conference and Banqueting is situated at the International Centre for Life, a pioneering science village in Newcastle upon Tyne. Access is via the main entrance on Central Parkway, just off Neville Street. Central Parkway is a private road which is accessible on foot from Neville Street and Railway Street. If you need to park on site, please get in touch to arrange this before you visit. On Foot If approaching from the Newcastle Central Station, turn left onto Central Parkway just before you reach Times Square, and you will find the entrance to Life Conference and Banqueting halfway down the road on your right. By Road Life is situated just a few minutes from the A1(M), linking it conveniently with London and the South, and Edinburgh and the North. Our multi-storey carpark provides over 400 secure parking spaces, with additional parking for disabled visitors just metres from our door. The Sat Nav reference for Times Square Car Park is NE4 7AD. By Rail Life is located just 200 metres from Newcastle Central Station, which provides high-speed rail links to London in under three hours, Edinburgh in one and a half hours and York in an hour. The Metro, Tyne and Wear’s light rail system, connects Newcastle, Gateshead, Sunderland, North Tyneside and South Tyneside. Regular direct trains between Central Station and Newcastle International Airport take less than half an hour. On Arrival From Life’s central location it’s easy to access all of the city centre’s shops, restaurants, hotels and visitor attractions on foot. The Metro system provides stress-free transport links across Tyne and Wear, including to the coast in less than half an hour.

The event is expected to attract a large number of high profile delegates from academia, industry, clinic and regulatory bodies. We can offer exhibition space to organisations that support the medical device manufacturing sector – email to enquire.

Poster presenters were emailed on Wednesday 9 December with guidelines for presentation of their poster and 1-minute pitch.
Download the poster guidelines (opens PDF) to save this information.
The running order for the presentations, including abstract/poster numbers, has now been finalised, download a copy here (opens PDF).

Speakers were emailed on Friday 8 January with guidelines for their presentation.
Download the speaker guidelines (opens PDF) to save this information.
The running order for the presentations, including abstract/poster numbers, has now been finalised, download a copy here (opens PDF).

Delegates were emailed on Thursday 14 January with joining instructions for the conference.
Download the joining instructions (opens PDF) to save a copy.

The MeDe Innovation Early Career Research (ECR) forum is dedicated to connecting all researchers, academic, clinical or industrial, linked to MeDe Innovation. The aims of this forum are to share experiences and expertise, support access to facilities and expertise available across the partners associated with MeDe Innovation to develop research capability and stimulate ideas for new collaborations. The next ECR meeting is taking place on 27th January in Newcastle, ahead of the MeDe Annual Conference on 28th. See the full programme and register now.

The MeDe Innovation Annual Conference 2016 abstracts book is now available to download (opens PDF).

MeDe Event