MeDe Innovation Third Annual Meeting: The Future of Manufacturing of Medical Devices

Date: January 28, 2016

Location: Centre for Life, Newcastle

MeDe Innovation Annual Conference 2016 –

The Future of Manufacturing of Medical Devices

MeDe Innovation (The EPSRC Centre for Innovative Manufacturing in Medical Devices) is addressing the future opportunities and challenges in the design and manufacture of medical devices. Our innovative design and manufacturing advances centres around three research focus areas: implants, biomaterials and regenerative devices for the treatment of musculoskeletal disease; where there is a growing demand for increased precision to deliver improved reliability and outcomes of medical devices. The centre activities are addressing two grand challenges:

Manufacturing at the point of need
Stratified design and manufacture

The global market for medical technologies is set to exceed $500bn per year by 2018, with a UK industry base valued at £18bn per year. Musculoskeletal implants, biomaterials and the emerging field of regenerative devices are major strengths in the UK, addressing a global market estimated to grow to $75bn by 2020. The needs of an ageing population, the expectations of fifty active years after fifty® and the growth in healthcare markets in developing economies provide a real opportunity for growth in this part of the medical device technology sector. However there are increased expectations and demands for enhanced lifetimes, cost effectiveness, more consistent patient outcomes and improved reliability. Stratification and increased precision, leading to improved reliability, is a key challenge in all areas of medicine and future opportunity for medical devices. As we approach the mid-term of MeDe innovation, the conference will report on progress and advances in research, innovation, and translation of its three focus areas:

New approaches to manufacturing at the point of need
Manufacturing regenerative devices, biological and biomimetic scaffolds
Stratified design and manufacture of orthopaedic implants

The conference will include presentations and posters from industry, regulators clinicians and academic researchers, panel discussions, poster pitches and networking opportunities.

Event programme

Download a copy of the event programme (opens PDF)

Time		Name
9.30	Registration and networking (tea and coffee available)
9.55	Welcome and introduction	Professor John Fisher, Centre Director
	*Session A: Manufacturing at the point of need – Chaired by Professors Kenny Dalgarno and Phil Coates*
10.00	Regenerative strategies in orthopaedics; right patient, right treatment, right time	Prof Andrew McCaskie – University of Cambridge
10.15	Manufacture and assembly of biopolymer-bioceramic hybrid composites	Miss Natacha Rodrigues – Newcastle University
10.30	Shape memory soft tissue fixations for arthroscopic delivery	Dr Fin Caton-Rose – University of Bradford
10.45	Development of materials for arthroscopic delivery	Mr Simon Partridge – Newcastle University
11.00	Design and fabrication of 3D printed POSS-nanocomposite-based lumbar cage for spinal fusion	Dr Tiziano Serra – University College London
11.15	Droplet based deposition for in clinic bioprinting	Dr Matthew Benning – Newcastle University
*11.30*	*1 minute poster elevator pitches*
	Harnessing micro-injection moulding and Poly-ether-ether-ketone (PEEK) to manufacture orthopaedic trauma implants that resist microbial colonisation	Dr Maria Katsikogianni – University of Bradford
	Processing and characterisation of novel bioceramic formulations using indirect powder-based 3D printing technology	Ms Elena Mancuso – Newcastle University
	Cell encapsulation for bio-ink formulation	Mr Ricardo Ribeiro – Newcastle University
	Compression screws for the fixation of small bones and bone fragments using biocompatible, bioresorbable, body-temperature reverting, plasticised shape memory polymers	Dr Brian Thomson – University of Bradford
	Apatite-Wollastonite glass ceramic scaffolds for osteochondral tissue engineering applications	Miss Sotiria Toumpaniari – Newcastle University
	Polyether ether ketone (PEEK) crystallisation phases analysis in microinjection moulding for anterior cervical decompression and fusion	Dr Cristina-Luminita Tuinea-Bobe – University of Bradford
	Viscoelastic mechanical optimisation of functionally graded cell-conducting materials for osteochondral implants	Dr Peter Twigg – University of Bradford
	Synthesis of tendon tissue-like grafts using a hybrid PHBV-Collagen material	Dr Sarah Upson – Newcastle University
	Controlled release of antibacterial drugs through in-situ crosslinked wet-spun collagen triple helices	Dr Muhammad Tarik Arafat – University of Leeds
	The development of stratified acellular biological scaffolds for osteochondral repair	Dr Hazel Fermor – University of Leeds
	Pre-clinical biomechanical evaluation of acellular biological scaffolds for tissue repair and replacement in the knee joint	Dr Anthony Herbert – University of Leeds
	Novel porous structures with internally-coated surfaces	Dr Andrew Kennedy – University of Nottingham
	Development of 3D artificial niches for regenerative medicine	Dr Ilida Ortega – University of Sheffield
	Fabrication of electrospun poly(caprolactone)/strontium-substituted bioactive glass composite membranes for bone tissue regeneration	Dr Martin Eduardo Santocildes Romero – University of Sheffield
	Resorbable, therapeutic ion leaching thin films for implant osseointegration	Mr Bryan Stuart – University of Nottingham
	Design of bespoke collagen hydrogels for chronic wound care	Dr Giuseppe Tronci – University of Leeds
	The next generation of simulators for stratified pre-clinical wear simulation of total knee replacements	Dr Abdellatif Abdelgaied – University of Leeds
	Enhanced preclinical testing of hip joint replacements	Dr Murat Ali – University of Leeds
	Manufacturing phosphate-glass fibre reinforced composite rods as bioresorbable intramedullary nails	Mr Fernando Barrera Betanzos – University of Nottingham
	PEEK Optima® as an Alternative Bearing Material to Cobalt Chrome in Total Knee Replacements	Dr Raelene Cowie – University of Leeds
	The determination of acetabular orientation: measured in different coordinate systems	Dr Xijin Hua – University of Leeds
	Subject-specific multi-validation of a Finite Element model of cervical functional spinal units	Dr Marlène Mengoni – University of Leeds
	The combined effect of head and cup centres mismatch and different cup inclination angles on the occurrence and severity of edge loading and wear in hip replacement	Mr Oscar O’Dwyer Lancaster-Jones – University of Leeds
	Wear of a total ankle replacement	Ms Alexandra Smyth – University of Leeds
11.55	MeDe Innovation Network Update	Rowan Grant – MeDe Innovation National Outreach Manager
12.00	*Lunch and poster viewing*
12.30-13.00	Poster presenters available from A7-B17
13.00-13.30	Poster presenters available from B18-C11
	*Session B: Manufacturing regenerative devices, biological and biomimetic scaffolds – Chaired by Professors Paul Hatton and David Grant*
	*Nanoparticles and medical devices*
13.30	Continuous hydrothermal synthesis of new nanoscale hydroxyapatite morphologies		Prof Ed Lester – University of Nottingham
13.35	Integrated molecular design of melt-processable bioresorbable engineering nanocomposites for health-care		Miss Kirsty Walton – University of Nottingham
13.40	Rapid mix preparation of biomimetic nanoscale hydroxyapatite for biomedical applications		Dr Caroline Wilcock – University of Sheffield
13.45	Biomimetic nano-structured materials for bone repair and regeneration – Industrial perspective		Dr Becci Goodchild – Ceramisys Ltd
13.50	Continuous hydrothermal synthesis of nanoparticles – Scaling up		Dr Selina Tang – Promethean Particles Ltd
	*Resorbable composite research*
13.55	Bioresorbable composites for bone fracture repair applications		Dr Ifty Ahmed – University of Nottingham
14.07	Development of bio-active glass products and production processes		Dr Malcolm Gledenning – Glass Technology Services Ltd
	*Spinal medical devices*
14.15	Trabecular directionality in three dimensional remodelling of bone graft substitute in cervical fusions		Dr Donal McNally – University of Nottingham
14.23	Porosity measurements in three dimensional remodelling of bone graft substitute in cervical fusions		Dr Scott Johnson – Cerapedics Inc
	*Surface modification and scaffolds*
14.30	Layer-by-layer: a bioengineered tool to enhance specific biological activities at nanoscale		Dr Piergiorgio Gentile – Newcastle University
14.37	Hydroxyapatite functionalised using a coupled heparin-binding peptide		Mr Joss Atkinson – University of Sheffield
14.44	Development of 3D polymer scaffolds for biomedical applications; degradation and compression properties		Dr Reda Felfel –
14.51	The JRI approach to innovation in Med Tech		Dr Sarrawat Rehman – JRI Orthopaedics Ltd
15.00	Break and poster viewing
	*Session C: Stratified design and manufacture of orthopaedic implants – Chaired by Professors John Fisher and Ruth Wilcox*
15.30	Overview of Challenge 1: Stratified design and manufacture of orthopaedic implants			Prof John Fisher – University of Leeds
15.35	Computational modelling of patient variation in the spine: a route to stratified device design and testing		Prof Ruth Wilcox and Prof Philippe Young – University of Leeds and Simpleware Ltd
15.45	Application of a computational and experimental wear simulation approach to new product development		Louise Jennings and Dr Adam Briscoe – University of Leeds and Invibio Ltd
15.55	Effect of surgical variations on the function and tribological performance of hip joint replacement		Dr Mazen Al Hajjar and Dr Jonathan Thompson – University of Leeds and DePuy Synthes
16.05	Panel discussion with Session C speakers
16.20	Closing comments		Prof John Fisher

Venue Details - Centre for Life, Newcastle

Life Conference and Banqueting is situated at the International Centre for Life, a pioneering science village in Newcastle upon Tyne. Access is via the main entrance on Central Parkway, just off Neville Street. Central Parkway is a private road which is accessible on foot from Neville Street and Railway Street. If you need to park on site, please get in touch to arrange this before you visit. On Foot If approaching from the Newcastle Central Station, turn left onto Central Parkway just before you reach Times Square, and you will find the entrance to Life Conference and Banqueting halfway down the road on your right. By Road Life is situated just a few minutes from the A1(M), linking it conveniently with London and the South, and Edinburgh and the North. Our multi-storey carpark provides over 400 secure parking spaces, with additional parking for disabled visitors just metres from our door. The Sat Nav reference for Times Square Car Park is NE4 7AD. By Rail Life is located just 200 metres from Newcastle Central Station, which provides high-speed rail links to London in under three hours, Edinburgh in one and a half hours and York in an hour. The Metro, Tyne and Wear’s light rail system, connects Newcastle, Gateshead, Sunderland, North Tyneside and South Tyneside. Regular direct trains between Central Station and Newcastle International Airport take less than half an hour. On Arrival From Life’s central location it’s easy to access all of the city centre’s shops, restaurants, hotels and visitor attractions on foot. The Metro system provides stress-free transport links across Tyne and Wear, including to the coast in less than half an hour.

Sponsorship opportunities

The event is expected to attract a large number of high profile delegates from academia, industry, clinic and regulatory bodies. We can offer exhibition space to organisations that support the medical device manufacturing sector – email info@mede-innovation.ac.uk to enquire.

Guidelines for poster presenters

Poster presenters were emailed on Wednesday 9 December with guidelines for presentation of their poster and 1-minute pitch.
Download the poster guidelines (opens PDF) to save this information.
The running order for the presentations, including abstract/poster numbers, has now been finalised, download a copy here (opens PDF).

Guidelines for speakers

Speakers were emailed on Friday 8 January with guidelines for their presentation.
Download the speaker guidelines (opens PDF) to save this information.
The running order for the presentations, including abstract/poster numbers, has now been finalised, download a copy here (opens PDF).

Delegate joining instructions

Delegates were emailed on Thursday 14 January with joining instructions for the conference.
Download the joining instructions (opens PDF) to save a copy.

Early Career Researcher (ECR) meeting - 27th January

The MeDe Innovation Early Career Research (ECR) forum is dedicated to connecting all researchers, academic, clinical or industrial, linked to MeDe Innovation. The aims of this forum are to share experiences and expertise, support access to facilities and expertise available across the partners associated with MeDe Innovation to develop research capability and stimulate ideas for new collaborations. The next ECR meeting is taking place on 27th January in Newcastle, ahead of the MeDe Annual Conference on 28th. See the full programme and register now.

Annual Conference Abstracts 2016

The MeDe Innovation Annual Conference 2016 abstracts book is now available to download (opens PDF).