National Capability Database | Capability Detail
Eileen Ingham
Decellularisation process for animal tissue
Capability Description
iMBE has extensive capability and know-how in a unique decellularisation process of animal tissues. Supported by an intellectual property portfolio on immunocompatible biomimetic natural scaffolds, and led by Professor Eileen Ingham in the Faculty of Biological Sciences, the University of Leeds are researching and developing functional soft tissue solutions for musculoskeletal and cardiovascular applications. These biomimetic natural acellular scaffolds can be implanted directly into patients and regenerated by the recipients own endogenous stem cells, or can be regenerated with differentiated or stem cells in vitro in bespoke physically interactive bioreactors. The Insitute aims to become one of the globally leading research centres for functional engineering of soft tissues for orthopaedic and cardiovascular applications.
Case Study
Research undertaken at the University of Leeds, carried out by Professor Eileen Ingham over the last ten years led to the incorporation of spin-out company Tissue Regenix (2006). Tissue Regenix uses its proprietary technology platform, dCELL®, to remove cells and other components from animal tissue allowing them to be used without anti-rejection drugs to replace worn out or diseased body parts. The company secured £25m private investment in 2011.
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